Developmental disorders of the human brain can cause epilepsy, intellectual disability and/or autism. We study the genetics and molecular biology of the developing cerebral cortex, the brain's largest structure, to advance the understanding, diagnosis and management of human neurological disease.
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Our research achievements are peer-reviewed and published in collaboration with other scientists and clinicians around the world.

Somatic mosaicism and neurodevelopmental disease

Somatic mutation in pediatric neurological diseases
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Our research is currently highlighted in various media such as The Atlantic and The Wall Street Journal. Check out what our current and former lab members are up to here!

Mike Lodato recognized with Cajal Club Award
Society for Neuroscience, San Diego, CA, November 2018

Postdoctoral fellow Mike Lodato was awarded the Kreig Cortical Explorer award by Cajal Club President Arturo Alvarez-Buylla. The leadership of the Cajal Club recognizes an outstanding neuroscientist studying the cerebral cortex and selected Mike as this year's winner for his work furthering our understanding of somatic mutations in the human brain. Mike feels extremely honored to receive this award from such a distinguished group, and is very thankful for the support from his family of his science, for the incredible group of collaborators he has had the fortune to work with while a member of the Walsh lab, and the fantastic mentorship and opportunities he continues to receive from his advisor Christopher Walsh.

Dr. Timothy Yu, Walsh Lab alumni, in the news! 
A tailormade drug developed in record time may save girl from fatal brain disease 
Saving Mila: How a tailor-made therapy, developed in a flash, may have halted a young girl’s rare disease 
Science and STAT October 2018

Visit TheYu Lab

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The Brain Development and Genetics Clinic offers consultation for children with developmental brain disorders and their families. Our physicians will review brain MRIs and medical history to help provide the best diagnosis and management options available.

Christopher Walsh, MD, PhD
Annapurna Poduri, MD, MPH
Ganesh Mochida, MD, PhD
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