Developmental disorders of the human brain can cause epilepsy, intellectual disability and/or autism. We study the genetics and molecular biology of the developing cerebral cortex, the brain's largest structure, to advance the understanding, diagnosis and management of human neurological disease.
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Our research achievements are peer-reviewed and published in collaboration with other scientists and clinicians around the world.

Aging and neurodegeneration are associated with increased mutations in single human neurons

Thoracic aortic aneurysm in patients with loss of function Filamin A mutations: Clinical characterization, genetics, and recommendations
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Our research is currently highlighted in various media such as The Atlantic and The Wall Street Journal. Check out what our current and former lab members are up to here!

Alissa D'Gama, MD, PhD, matched at Boston Children's Hospital, for her pediatrics residency. Congratulations!

Allen Chen, MD, PhD, matched at New York-Presbyterian/Weill Cornell for his internal medicine research residency. Congratulations!

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The Brain Development and Genetics Clinic offers consultation for children with developmental brain disorders and their families. Our physicians will review brain MRIs and medical history to help provide the best diagnosis and management options available.

Christopher Walsh, MD, PhD
Annapurna Poduri, MD, MPH
Ganesh Mochida, MD, PhD
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