Developmental disorders of the human brain can cause epilepsy, intellectual disability and/or autism. We study the genetics and molecular biology of the developing cerebral cortex, the brain's largest structure, to advance the understanding, diagnosis and management of human neurological disease.
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Our research achievements are peer-reviewed and published in collaboration with other scientists and clinicians around the world.

SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL

Recessive gene disruptions in autism spectrum disorder
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Our research is currently highlighted in various media such as The Atlantic and The Wall Street Journal. Check out what our current and former lab members are up to here!

Dr. Saumya Shekhar Jamuar appointed Head of Genomic Medicine Centre at SingHealth Duke‚ąíNUS Academic Medical Centre, Singapore. Congratulations! May 2019

Kelly Girskis, PhD successfully defended her thesis, titled: "What Makes Us Human?: Evolution of the Human Genome, Species-Specific Gene Regulation, and the Development of the Human Cerebral Cortex." in the Harvard University Program in Neuroscience. Congratulations!  April 2019 

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The Brain Development and Genetics Clinic offers consultation for children with developmental brain disorders and their families. Our physicians will review brain MRIs and medical history to help provide the best diagnosis and management options available.

Christopher Walsh, MD, PhD
Annapurna Poduri, MD, MPH
Ganesh Mochida, MD, PhD
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