Developmental disorders of the human brain can cause epilepsy, intellectual disability and/or autism. We study the genetics and molecular biology of the developing cerebral cortex, the brain's largest structure, to advance the understanding, diagnosis and management of human neurological disease.
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Our research achievements are peer-reviewed and published in collaboration with other scientists and clinicians around the world.

SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL

Recessive gene disruptions in autism spectrum disorder
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Our research is currently highlighted in various media such as The Atlantic and The Wall Street Journal. Check out what our current and former lab members are up to here!

Mike Lodato appointed to the Allen Institute's Next Generation Leadership Council!

The Next Generation Leaders Program at the Allen Institute for Brain Science aims to formally recognize the importance of fresh and creative contributions to neuroscience from early-stage researchers. Mike will serve a three-year term as a Next Generation Leader, taking part in Advisory Council Meetings at the Allen Institute in Seattle. He is incredibly honored to receive this opportunity as he culminates a fantastic postdoctoral fellowship here at the Walsh lab to embark on a new journey as the head of his own lab at the University of Massachusetts Medical School in Worcester, MA! Aug 2019

Christopher A. Walsh, MD, PhD
HHMI Investigator Profile, Howard Hughes Medical Institute

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The Brain Development and Genetics Clinic offers consultation for children with developmental brain disorders and their families. Our physicians will review brain MRIs and medical history to help provide the best diagnosis and management options available.

Christopher Walsh, MD, PhD
Annapurna Poduri, MD, MPH
Ganesh Mochida, MD, PhD
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